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This approach has increased access to quality medicines by 40% while reducing regulatory costs by 35%, providing a practical model for SRA-reliance implementation [41,42]

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However, other mammals, such as guinea pigs and humans, have much higher levels of hepatic GGT (Hinchman and Ballatori, 1990, Hinchman et al., 1991, Hinchman et al., 1993, Hinchman et al., 1998), and therefore, metabolic pathways and trafficking of mercapturate intermediates may vary from species to species