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In addition, a special mu loop (EAGGPPDFS) between β 2 and α 2 was found

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Among the multiple pathologic mechanisms potentially responsible for DOPAn loss, protein aggregation (e.g., α-synuclein–αSyn, ubiquitin), proteasomal dysfunction, inflammation, mitochondrial dysfunction, reactive oxygen species (ROS) and nitrogen oxygen species (NOS), reduction in the anti-oxidant defense (GSH, reduced glutathione