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BPC-157 (Body Protection Compound-157, CAS 137525-51-0, ~1419 g/mol) is a synthetic pentadecapeptide studied in vitro and in preclinical models for interactions with nitric oxide signalling, VEGF and EGF growth-factor pathways, and cytoprotection

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report that activating Nrf2 and enhancing its nuclear translocation can inhibit Ox-LDL-induced ferroptosis in macrophages and resist ferroptosis in ApoE −/− animals on a high-fat diet (Luo et al., 2024)