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Ascorbate supplementation markedly improves the differentiation of midbrain derived neural stem cell against dopaminergic neurons, which is associated with the TET-mediated 5hmC generation and Jmjd3 catalyzed loss of H3K27m3 (He et al., 2015)

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Address underlying causes alongside treatment: wear sunglasses to reduce squinting, manage allergies that cause eye rubbing, and ensure adequate hydration