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Cur binds strongly to the α-syn monomer, with a dissociation constant of 10 −5 M, and disrupts the long-range interactions inside the peptide chain, increasing the reconfiguration rate of the molecule, thus completely inhibiting both oligomerization and fibrillization
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doi: 10.1007/978-1-4614-0634-1_9 [DOI] [Google Scholar] 19
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