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These complexes also coordinate bridging [2Fe-2S] clusters, with BolA2 contributing a histidine ligand to coordinate the cluster(s) ( in vitro ( Genetic studies in yeast, fish, and human cells suggest that Grx3 orthologs have similar but distinct roles in cytosolic iron delivery
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This protective effect is attributed to the ability of Lactobacillus casei Shirota (LcS) to stimulate the secretion of TNF-α and interleukin-12 (IL-12), cytokines that are well-established drivers of enhanced NK cell cytotoxic activity (194)
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