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Retatrutide fits hypotheses about the coupled GIPR, GLP-1R and GCGR signalling architecture [2](#ref-2)[6](#ref-6)
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Although the importance of phosphorylated p22 phox in neutrophils' NADPH oxidase activity has not been studied to our knowledge, work in CHO cells suggested that PMA-dependent phosphorylation of p22 phox at threonine 147 is important for its interaction with p47 phox (Lewis et al., 2010)
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