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Metastatic malignant melanoma in the bone marrow
Chaturvedi RK, Beal MF.Mitochondrial approaches for neuroprotectionAnn N Y Acad Sci20081147395412 102
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Second, in the intrinsic or mitochondria-mediated pathway, intracellular stress signals lead to release of cytochrome c from the mitochondrial intermembrane space into the cytosol, where it binds to the apoptotic protease activating factor-1 (Apaf-1)
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