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Taking into consideration the previously determined value for [GSH] 2 :[GSSG] in the ER of 83 mM, this translates into a total glutathione concentration in the ER ([GS tot ]=[GSH]+2[GSSG]) of greater than 15 mM
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Glutamate-evoked redox state alterations are involved in tissue transglutaminase upregulation in primary astrocyte cultures
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