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By engaging and modulating cardinal molecular circuits—most notably NF-κB, the NLRP3 inflammasome, MAPK cascades, and T-cell lineage specification—statins orchestrate a concerted suppression of pro-inflammatory signalling that traverses the domains of metabolic dysregulation, vascular pathology, and oncogenesis

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Finally, Xu, X.’s study was conducted in postmenopausal women whose Se intake was greater than or equal to baseline levels, and the subject’s condition was another major limitation of this trial