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In 2014, researchers showed that knocking down the NNMT gene protected mice against diet induced obesity (the 2014 Nature paper reporting that nicotinamide N-methyltransferase knockdown protects against diet-induced obesity)
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Chandyo RK, Ulak M, Kvestad I, Shrestha M, Ranjitkar S, Basnet S, Hysing M, Shrestha L, Strand TA
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