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110 This suggests that CSCs may emerge through multiple, context-dependent mechanisms that are influenced by both intrinsic (e.g., genetic or epigenetic alterations) and extrinsic (e.g., microenvironmental signals) factors
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Additionally, dietary plant secondary metabolites such as polyphenols have shown promise in modulating immune responses, gut microbiome, and mitigating inflammatory processes implicated in lupus pathogenesis [14]
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