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130 The mechanisms by which PEV cargo reaches functional compartments within host cells are increasingly understood
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Agents that inhibit the cystine uptake via the cystine/glutamate antiporter (system x c - ) (e.g., sulfasalazine) or directly deplete the GSH from plasma (e.g., cyst(e)inase) triggers ferroptosis and arrests tumorigenesis [224, 225]
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