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The DEGs downregulated in GLA-mutant Fabry kidney organoids included various genes involved in inflammation and oxidative stress
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5α-Reductase inhibitor 5α-Reductase inhibitors ( 5-ARIs ), also known as dihydrotestosterone ( DHT ) blockers , are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss
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