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Table 1 Folate-mediated therapeutics and disease states under investigation Challenges in Folate Receptor-Targeted Therapy Despite the innovative nature and potential of targeting the folate receptor, several challenges hinder broader application and efficacy: Heterogeneity of Tumor Expression: The expression of FRα varies widely among different tumors and even within the same tumor type, which can affect the outcome of folate-based therapies
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Evaluation of high dose N- acetylcysteine on airway inflammation and quality of life outcomes in adults with bronchiectasis: a randomised placebo-controlled pilot study
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