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Therapeutic efficacy depends on optimal integration of target antigen selection, antibody format, linker stability, payload potency, and conjugation chemistry ( Figure 1 )

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Both probiotics and prebiotics have a variety of biological actions, including outcompeting pathogenic microorganisms in the digestive tract, inactivating harmful metabolites, producing powerful bioactive molecules (short-chain fatty acids), modulating immune and metabolic signaling, improving overall digestive tract function, and enhancing central nervous system effects through the gut–brain axis