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A recent synthesis of preclinical evidence on mushroom polysaccharides—including those from Hericium, Ganoderma, and Inonotus—supports the view that these macromolecules act as multi-target modulators of the gut–brain axis by converging effects on the microbiota, oxidative-stress control, mitochondrial function, and neuroinflammation across AD and PD models [141]
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