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glutathione sulfur amino acid Frontiers NAD+ Precursors and Antioxidants
NAD+ Precursors and Antioxidants for the Treatment of Amyotrophic Lateral Sclerosis - PMC
Researchers working with these compounds must comply with their institutional review board (IRB) requirements and applicable local and federal regulations
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Various strategies can potentially mitigate ferroptosis in AD, such as antioxidant therapy using compounds like vitamin E or Lip-1 to reduce neurodegeneration, iron chelation therapy to control iron levels and limit the generation of ROS, modulation of glutamate signaling pathways to address excitotoxicity, regulation of lipid metabolism to prevent LPO, and activation of GPX4 to safeguard cells against LPO and ferroptosis (Park et al., 2021)
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