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Moreover, given that the ability of placental to supply nutrients for fetal growth and development depends on gestational age 19 , and that maternal liver enzyme levels fluctuate dynamically throughout pregnancy, the gestational week of measurement may be an important confounding factor affecting the association between liver biomarkers and neonatal birth weight

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Moreover, alterations in DNA methylation at specific genomic loci have been associated with difficulty conceiving, and DNA methylation and gene transcription patterns may be predictive of assisted reproductive technology (ART) success rates [121,122,123]