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rxlist.com Austedo ® Keywords Valbenazine Trade Name: Ingrezza ® Drug Class: Rx of Tardive dyskinesia (monoamine depletor) Mechanism of Action: a selective competitive inhibitor of VMAT2, similar to tetrabenazine the monoamine vesicular monoamine uptake transporter (VMAT2) transports (loads) cytoplasmic monoamine neurotransmitters (dopamine, norepinephrine, histamine, serotonin) into presynaptic storage vesicles found in sympathetic nerve terminals
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This progressive oxidative burden is widely believed to represent a critical mechanistic bridge linking normal aging to the onset and progression of AD [4, 5, 7, 9, 10]
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