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5C), but most of the lipid loading was observed in HIV fused macrophages, which are the cells that survive infection and silence viral replication (Fig

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Conversely, its transport across the inner mitochondrial membrane occurs through a specific transporter composed of two proteins named MPC1 and MPC2 (Mitochondrial Pyruvate Carrier), which form a hetero-oligomeric complex in the membrane, catalyzing a pyruvate/H + symport towards the matrix

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