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360 Since transcriptional induction of β2-integrin gene expression plays a vital role in macrophage function, work was undertaken to identify the causative molecular mechanisms
GMC: RX
Size (mL):3mL
Yao et al., has reported associations between Val66Met polymorphism and increased susceptibility to conditions such as schizophrenia and AD ( Several natural products were screened against the BDNF variant (V66M) such as Vitamin D3 (Tveden-Nyborg, 2021) and Quercetin ( BDNF crystallographic structure from the Protein Data Bank (PDB) database (PDB ID: 1BND) was chosen as the modeling reference (RCSB PDB, 2026) BDNF-ligand complexes were analyzed for their binding energy, interaction, stability, toxicity, and visualization using a variety of tools, including AUTODOCK VINA, BIOVIA discovery studio, PyMOL, CB-dock, IMOD server, Swiss ADEMT, and Swiss predict ligands target
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