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These models for species with up to three ionizable centers were summarized in a 2004 review article by Poole.52 The pK a may be determined by numerically fitting the resulting relations to a plot of mobility versus pH through nonlinear regression, as shown in Figure 9 for the case of 2-aminopyridine.54 The shape of these curves depends only upon m d and the position depends only upon pK a , therefore this regression directly yields the pK a value(s) of interest

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[147] In Week 15 against the Philadelphia Eagles, Hopkins recorded nine catches for 169 yards and a touchdown during the 33–26 win