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A typical acute injury protocol begins with 0.25 mg twice daily for the first week, reduces to 0.5 mg once daily for weeks two through four, then continues at 0.25 mg daily for weeks five and six if needed

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The evolutions in the field of drug discovery open the way to a new generation of senolytic therapies, such as immunological approaches (CAR-T cells, Antibody-Drug Conjugated or vaccines), which require preliminary steps of research to identify markers specifically expressed on senescent cells, demonstrating promising specific effects