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Recent studies have shown that the gut and genital tract microbiota play an important role in regulating the host immune-metabolic axis, particularly in iron metabolism and ferroptosis pathways, providing a new perspective for understanding the pathological progression of EMS from the holistic dimension of “microecology–iron metabolism–cell death.” It should be noted that existing evidence is insufficient to definitively determine whether EMS drives microbiome imbalance first or whether microbial imbalance precedes and promotes the occurrence of EMS

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Lot #:Lot #: N9IPA10/0528

Of note, transcription of cyclin-dependent kinase inhibitor, p21 ( CDNK1A ) was significantly upregulated in response to GSTO1 knockdown while that of the cell cycle regulatory proteins cyclin D1 ( CCND1 ), cyclin E1 ( CCNE1 ), as well as Myc were found downregulated (GEO accession No