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When your body may rely only on fatty acids instead of glucose for energy, a carrier of one ACADM mutation may find that their blood sugar drops and they feel weak.[ref][ref][ref][ref] People with one copy of the mutation may have no problems at all under normal conditions since fatty acid oxidation should still work — just at a less-than-optimal level

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Chambon (Igbmc, France) ( +/+ -SCID mice (which suffer from spontaneous and chronic death of hepatocytes) with 0.7 x 10 6 cryopreserved primary human hepatocytes (donor C342, Lonza), via intrasplenic injection