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The brain is constituted by a preponderance of microglia and astrocytes, these glial cells are essential in the Central Nervous System (CNS), with microglia functioning as innate immune cells involved in surveillance and defense, while astrocytes modulate neuronal communication, maintain the extracellular environment, and regulate inflammatory signaling (Schwarz and Bilbo, 2012)

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Endogenous deficiency of glutathione as the most likely cause of serious manifestations and death in COVID-19 patients