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Nevertheless, monotherapeutic ICIs still face bottlenecks including limited response rates and the frequent development of drug resistance in most solid tumors
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126 Bioactive oxidized phospholipids (oxPLs) bind to LRP6 in bone marrow mesenchymal stem cells (BMSCs) and induce their endocytosis, contributing to the inhibition of Wnt signalling and diminishing osteoblast differentiation ability
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