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For instance, microfluidic-fabricated composite NPs co-loaded with a GLP-1 analogue and sitagliptin reduced fasting glucose levels 1.7-fold more effectively than either agent alone in db / db mice, with sustained HbA1c reductions over six weeks [420]
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Moreover, treatment with human AM/AMBP-1 in a rat model of renal I/R injury significantly alleviated organ damage and inflammatory response [ 93 ]
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