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doi: 10.1016/j.jconrel.2016.01.056
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interestingly, genetic-mediated deletion of PINK1 and Parkin in α-synuclein transgenic mice (A53T) crossed with PINK1 or Parkin knockout mice worsened mitochondrial pathology, suggesting that PINK1-Parkin is cytoprotective to remove dysfunctional mitochondria [47]
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