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As a whole, this evidence indicates that gliotransmission modulates the activity of astrocytes and neuronal circuits (projecting and interneurons) and appears to be a widespread mechanism in the brain
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This latter paper shows for the first time that CBD seems both to normalize the D3 receptor expression in gestational methylazoxymethanol acetate (MAM) model of SCZ and to bind preferentially to dopamine D3 receptors, as novel potential mechanism of action
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