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Importantly, patterns of age-related muscle loss appear to be different between sexes, with men demonstrating a greater rate of relative loss in muscle mass with age and females having a greater prevalence for sarcopenia–likely due to males having a higher muscular reserve compared to females (de Jong et al., 2023)
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They further revealed that CTGF can trigger the migration of monocytes in OA by enhancing monocyte chemoattractant protein-1 (MCP-1) expression through interaction with integrin avβ5 (142)
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