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Selected TKIs, such as EGFR targeted covalent inhibitors, have been designed to overcome issues of treatment resistance due to specific mutations in NSCLC
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Tunel Assay Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) method, is used for detect apoptotic DNA strand breaks, was carried out with the In Situ Cell Apoptosis Detection Kit, AP (Sangon Biotech, Shanghai)
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