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The adhesion molecule CD44 variant (CD44v) is a protein recently found to interact with SLC7A11, and it was reported that [52] when there is a deficiency of CD44v, the cell surface localization and stability of SLC7A11 are impaired, leading to intracellular GSH depletion, ROS induction and suppression of the progression of gastrointestinal tumors

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33 In cats with chronic EHBDO, the common bile duct will become widely dilated and tortuous, a finding easily seen on abdominal ultrasonography but a problem not easily managed (FIGURE 23-56, FIGURE 23-57 )