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[Fig 1] The presence of diverticula occurs more frequently in the colon, specifically in the sigmoid and descending

nicotinamide-adenine-dinucleotide

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maintenance 20 mg daily ▶ BY INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION Adult: 40 mg daily continue until oral administration possible, injection to be given over at least 3 minutes Severe oesophagitis ▶ ▶ BY MOUTH Adult: 40 mg once daily for 8 weeks, continue as maintenance treatment if appropriate Severe oesophagitis, refractory to initial treatment ▶ ▶ BY MOUTH Adult: 40 mg twice daily Gastro-oesophageal reflux disease (in the absence of oesophagitis) ▶ ▶ BY MOUTH ▶ ▶ ▶ Child 1–11 years (body-weight 10 kg and above): 10 mg once daily for up to 8 weeks Child 12–17 years: 20 mg once daily for up to 4 weeks Adult: 20 mg once daily 4 or 8 weeks, then 20 mg daily if required ▶ BY INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION Adult: 20 mg once daily continue until oral administration is possible, injection to be given over at least 3 minutes Uninvestigated dyspepsia ▶ ▶ BY MOUTH Adult: 20 mg once daily for 4 weeks Zollinger–Ellison syndrome ▶ ▶ BY MOUTH Adult: Initially 40 mg twice daily, adjusted according to response