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Double-strength saline solution should be avoided even in cases of severe hyponatraemia, because rapid correction of sodium depletion may cause central pontine myelinolysis

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Size:0.5 mL Vial

This dual strategy not only influences the protective and permeation-enhancing capabilities of nanoparticles for example (liposomes, niosomes, solid lipid nanoparticles, polymeric nanoparticles), but also capitalizes on the controlled release, improved mucosal adhesion and increase the residence time provided by the matrix [48]